EFFECTIVENESS OF VR THERAPY USING THE VRNOW SIMULATOR FOR PHANTOM LIMB PAIN FOLLOWING LOWER LIMB AMPUTATION

Autor

DOI:

https://doi.org/10.32782/2522-1795.2026.20.1.6

Słowa kluczowe:

lower limb amputation; pain management; rehabilitation intervention; functional training; virtual reality; military personnel

Abstrakt

Under conditions of martial law in Ukraine, a marked increase in the incidence of traumatic amputations has been observed, which highlights the urgent need for effective rehabilitation strategies. Military amputees, despite their high motivation to return to an active and meaningful life, frequently experience pronounced pain syndromes, including residual limb pain and phantom limb pain. The intensity and chronicity of pain may substantially limit physical activity, hinder prosthetic training, and adversely affect psycho-emotional well-being. In this context, effective pain management constitutes a key prerequisite for successful rehabilitation, as pain reduction provides the foundation for functional recovery and reintegration into an active lifestyle. Mirror therapy demonstrates limited clinical effectiveness and is associated with a number of anatomical and motivational barriers. Virtual reality is therefore considered an alternative approach to sensorimotor reintegration, offering enhanced feedback and improved patient compliance. Accordingly, investigation of the effectiveness of VR therapy represents a timely and well-justified direction in contemporary rehabilitation science.

The objective of the study is to demonstrate the effectiveness of VR therapy using the VRNOW simulator in the management of phantom limb pain in patients following lower limb amputation.

Materials and Methods. The study was conducted at the Medical Centre “Path to Health” LLC during 2024–2025 and consisted of two 14-day treatment courses. A total of 36 patients after lower limb amputation participated in the study during the third (pre-prosthetic rehabilitation) and fourth (prosthetic rehabilitation) stages of the rehabilitation process. The mean age of the male participants was 41,2±8 years; all patients were military personnel. Transtibial amputations accounted for 63,9% (n=23) of cases, while transfemoral amputations accounted for 36,1% (n=13). Phantom pain dynamics and quality of life were assessed using the Phantom and Stump Pain Questionnaire (PSPQ), the SF-36 Health Survey, and a pain diary. VR therapy using the VRNOW simulator was administered twice daily, with session durations of 20-30 minutes during Stage III and 35-45 minutes during Stage IV, based on an individualised selection of virtual tasks.

Results. VR therapy resulted in clinically significant improvements across multiple pain parameters. According to the PSPQ (NRS index), the number of patients with moderate residual limb pain decreased from 22 to 6, while 33,3% of patients (n=12) reported complete pain relief (mean score 1,83±0,28; p≤0,001). A substantial reduction was also observed in the number of patients with persistent phantom limb pain (from 30 to 8), with complete pain resolution reported in 44,4% of cases (n=16; mean score 1,44±0,28; p≤0,001). In addition, a marked decrease in persistent phantom sensations was noted, along with the disappearance of intrusive symptoms. Statistically significant improvements were recorded in most SF-36 domains, with the greatest increase observed in the bodily pain scale (BP +28,4 points; p≤0,001), confirming a pronounced analgesic effect. The increase in the Global Health Index (GHI +12,0 points; p≤0,01) reflects a clinically meaningful transition to a higher level of functioning.

Conclusions. The use of VR therapy with the VRNOW simulator in patients after lower limb amputation contributes to the reduction of residual limb pain, phantom limb pain, and phantom sensations through staged sensorimotor stimulation and restoration of neural connections. During Stage III (pre-prosthetic rehabilitation), the application of the Virtual Limb mode, isometric exercises, and virtual interaction with objects facilitates the formation of controlled visuomotor feedback, resulting in reduced pain intensity, attenuation of phantom sensations, and normalisation of perception of the missing limb. During Stage IV (prosthetic rehabilitation), the therapeutic focus shifts towards the restoration of proprioception, gait symmetry, and dynamic balance, which collectively enhance functional capacity and improve quality of life in patients after lower limb amputation.

Bibliografia

1. Bochkova, N., Petsenko, N., & Satanovska, K. (2024). Osoblyvosti fizychnoi reabilitatsii viiskovosluzhbovtsiv pry amputatsii nyzhnikh kintsivok [Features of physical rehabilitation of servicemen with lower limb amputation]. Naukovyi chasopys Ukrainskoho derzhavnoho universytetu imeni Mykhaila Drahomanova, 3(176), 127–131. https://doi.org/10.31392/UDU-nc.series15.2024.3K(176).27 [in Ukrainian].

2. Brazhaniuk, A., & Serman, S. (2025). Vplyv i komponenty doproteznoi reabilitatsii patsiientiv pislia amputatsii nyzhnikh kintsivok [Impact and components of pre-prosthetic rehabilitation of patients after lower limb amputation]. Physical Culture and Sport: Scientific Perspective, 1(1), 176–182. https://doi.org/10.31891/pcs.2025.1(1).23 [in Ukrainian].

3. Matiash, M.M. (2023). Medyko-psykholohichna reabilitatsiia viiskovosluzhbovtsiv v umovakh rosiisko-ukrainskoi viiny: etnopsykholohichnyi dyskurs, natsionalni perspektyvy hromadskoho zdorovia [Medical and psychological rehabilitation of servicemen in the conditions of the Russian-Ukrainian war: ethnopsychological discourse, national public health perspectives]. Ukrainskyi medychnyi chasopys, 1(153), 6–9. https://doi.org/10.32782/2311-8458/2025-1-4 [in Ukrainian].

4. Merzlikina, O.A., Triasun, Yu.R., & Kovalenchenko, V.F. (2024). Prohrama fizkulturno-sportyvnoi reabilitatsii viiskovosluzhbovtsiv pislia amputatsii nyzhnikh kintsivok u reabilitatsiinomu tsentri [Program of physical culture and sports rehabilitation of servicemen after lower limb amputation in a rehabilitation center]. Naukovyi chasopys Ukrainskoho derzhavnoho universytetu imeni Mykhaila Drahomanova, 3K(176), 326–330. https://doi.org/10.31392/UDU-nc.series15.2024.3K(176).71 [in Ukrainian].

5. Nikanorov, O., & Krykunov, O. (2023). Osoblyvosti fizychnoi terapii viiskovosluzhbovtsiv z amputatsiieiu nyzhnikh kintsivok [Features of physical therapy of servicemen with lower limb amputation]. Sportyvna medytsyna, fizychna terapiia ta erhoterapiia, (2), 84–87. https://doi.org/10.32652/spmed.2023.2.84-87 [in Ukrainian].

6. Odynets, T., Bielov, Ye., & Vaniuk, O. (2023). Fizychna terapiia viiskovosluzhbovtsiv pislia amputatsii [Physical therapy of servicemen after amputation]. Physical Culture and Sport: Scientific Perspective, 4, 46–49. https://doi.org/10.31891/pcs.2023.4.6 [in Ukrainian].

7. Yanchynskyi, O., Lapyshchak, I., Budzyn, V., & Zharska, N. (2025). Spetsyfika reabilitatsii osib pislia amputatsii nyzhnikh kintsivok: ohliad naukovoi literatury v period 2022–2024 rokiv [Specifics of rehabilitation of persons after lower limb amputation: review of scientific literature in 2022–2024]. Fizychna aktyvnist, zdorovia i sport, 1(37), 55–64. https://doi.org/10.32782/2221-1217-2025-1-08 [in Ukrainian].

8. Aldington, D., et al. (2014). A survey of post-amputation pains in serving military personnel. J R Army Med Corps, 160(1), 38–41. https://doi.org/10.1136/jramc-2013-000069

9. Ambron, E., Buxbaum, L.J., & Miller, A. (2021). Virtual Reality Treatment Displaying the Missing Leg Improves Phantom Limb Pain: A Small Clinical Trial. Neurorehabilitation and Neural Repair, 35(12), 1100–1111. https://doi.org/10.1177/15459683211054164

10. Boomgaardt, J., Dastan, K., Chan, T., et al. (2022). An Algorithm Approach to Phantom Limb Pain. Journal of Pain Research, 15, 3349–3367. https://doi.org/10.2147/JPR.S355278

11. Burholt, V., & Nash, P. (2011). Short Form 36 (SF-36) Health Survey Questionnaire: normative data for Wales. Journal of Public Health (Oxford, England), 33(4), 587–603. https://doi.org/10.1093/pubmed/fdr006

12. Chung, S.M., Wang, J.C., Lin, C.R., et al. (2025). Beyond traditional therapies: a network meta-analysis on the treatment efficacy for chronic phantom limb pain. Regional Anesthesia and Pain Medicine, 50(3), 213–224. https://doi.org/10.1136/rapm-2023-105104

13. Chung-Wai Cheung, J., Sze Ki Cheung, D., & Ni, M. (2023). X-reality for phantom limb management for amputees: A systematic review and meta-analysis. Engineered Regeneration, 4(2), 134–151. https://doi.org/10.1016/j.engreg.2023.02.002

14. Eldaly, A.S., Avila, F.R., Torres-Guzman, R.A., et al. (2022). Virtual and Augmented Reality in Management of Phantom Limb Pain: A Systematic Review. HAND, 19(4), 545–554. https://doi.org/10.1177/15589447221130093

15. Flor, H. (2002). Phantom limb pain: characteristics, causes, and treatment. The Lancet Neurology, 1(3), 182–189. https://doi.org/10.1016/S1474-4422(02)00074-1

16. Hali, K., Manzo, M.A., & Koucheki, R. (2024). Use of virtual reality for the management of phantom limb pain: a systematic review. Disability and Rehabilitation, 46(4), 629–636. https://doi.org/10.1080/09638288.2023.2172222

17. Kaur, A., & Guan, Y. (2018). Phantom limb pain: A literature review. Chinese Journal of Traumatology, 21(6), 366–368. https://doi.org/10.1016/j.cjtee.2018.04.006

18. Keesom, E., Lidström-Holmqvist, K., & Ortiz-Catalan, M. (2025). Reducing phantom limb pain using phantom motor execution enabled by augmented and virtual reality: participants' perspectives on an innovative treatment. Disability and Rehabilitation, 47(12), 3078–3087. https://doi.org/10.1080/09638288.2024.2413179

19. Kuffler, D.P. (2023). Evolving techniques for reducing phantom limb pain. Experimental Biology and Medicine (Maywood), 248(7), 561–572. https://doi.org/10.1177/15353702231168150

20. Lendaro, E., Van der Sluis, C.K., Hermansson, L., et al. (2025). Extended reality used in the treatment of phantom limb pain: a multicenter, double-blind, randomized controlled trial. Pain, 166(3), 571–586. https://doi.org/10.1097/j.pain.0000000000003384

21. Liberov, V., & Liberov, K. (2023). Ukrainians who have lost one or more limbs since the start of the war with Russia. The Wall Street Journal. https://www.wsj.com/articles/in-ukraine-a-surge-in-amputations-reveals-the-human-cost-of-russias-war-d0bca320.

22. LoMartire, R., Äng, B.O., Gerdle, B., & Vixner, L. (2020). Psychometric properties of Short Form-36 Health Survey, EuroQol 5-dimensions, and Hospital Anxiety and Depression Scale in patients with chronic pain. Pain, 161(1), 83–95. https://doi.org/10.1097/j.pain.000000000000170019

23. Ol, H.S., Van Heng, Y., Danielsson, L., & Husum, H. (2018). Mirror therapy for phantom limb and stump pain: a randomized controlled clinical trial in landmine amputees in Cambodia. Scandinavian Journal of Pain, 18(4), 603–610. https://doi.org/10.1515/sjpain-2018-0042

24. Olszak, J., Zalewa, K., Bartoszek, L., et al. (2024). Phantom pain – etiopathogenesis and treatment methods. Journal of Education, Health and Sport, 75, 56000. https://doi.org/10.12775/JEHS.2024.75.56000

25. Protez Hub. (2023). Doslidzhennia haluzi protezuvannia kintsivok v Ukraini. Analiz ta zvit [Research on the limb prosthetics sector in Ukraine. Analysis and report]. Retrieved from https://protezhub.com/blog/doslidzhennya-haluzi-protezuvannya-kintsivok-v-ukrayini-analiz-ta-zvit-protez-hub [in Ukrainian].

26. Rich, T.L., Falbo, K.J., Phelan, H., et al. (2024). Clinician perspectives on postamputation pain assessment and rehabilitation interventions. Prosthetics and Orthotics International, 48(4), 441–447. https://doi.org/10.1097/PXR.0000000000000284

27. Winter, C., Fritsche, K., Karl, A., Huse, E., Larbig, W., Grüsser, S.M., & Flor, H. (2001). Ein strukturiertes Interview zur Erfassung von Phantom- und Stumpfphänomenen nach Amputation [The phantom and stump phenomena interview (PSPI)]. Der Schmerz, 15(3), 172–178. https://doi.org/10.1007/s004820170019

28. Yevchenko, D.O., et al. (2023). The mirror therapy effectiveness as a part of physical rehabilitation program of servicemen after lower limb amputation due to mine-explosive injury. Ukrainian Journal of Military Medicine, 4(4), 60–68. https://doi.org/10.46847/ujmm.2023.4(4)-060 [in Ukrainian].

29. Ziegler-Graham, K., MacKenzie, E.J., Ephraim, P.L., et al. (2008). Estimating the prevalence of limb loss in the United States: 2005 to 2050. Archives of Physical Medicine and Rehabilitation, 89(3), 422–429. https://doi.org/10.1016/j.apmr.2007.11.005

Opublikowane

2026-04-30

Jak cytować

Zviriaka, O. M., Svyst, O. M., & Kerestei, V. V. (2026). EFFECTIVENESS OF VR THERAPY USING THE VRNOW SIMULATOR FOR PHANTOM LIMB PAIN FOLLOWING LOWER LIMB AMPUTATION. Rehabilitacja I Rekreacja, 20(1), 52–61. https://doi.org/10.32782/2522-1795.2026.20.1.6

Numer

Dział

TERAPIA I REHABILITACJA

Podobne artykuły

1 2 3 4 5 6 7 8 9 10 > >> 

Możesz również Rozpocznij zaawansowane wyszukiwanie podobieństw dla tego artykułu.